Sunday, February 3, 2013

Bus hits overpass in Boston, injuring dozens

BOSTON (AP) ? A charter bus carrying high school students from Pennsylvania crashed when it attempted to pass under a low bridge in Boston on Saturday night, injuring more than 30 people, several seriously, and leaving some trapped inside for hours, authorities said.

The students had been in the area to visit Harvard University. The bus, which was carrying 42 students and adult chaperones, was heading back to the Philadelphia area when it struck an overpass on Soldier's Field Road, a major crosstown road, at around 7:30 p.m., Massachusetts State Police said.

Authorities said the Calvary Coach bus did not belong on that road, which was not authorized for over-sized vehicles, and State Police were investigating whether charges were warranted against the driver, who apparently failed to see a sign prohibiting the vehicle from taking that route.

Ray Talmedge, owner of the Philadelphia-based Calvary Coach Bus company, said his driver was being interviewed by police. Talmedge said the driver, who also drives a school bus, didn't know about the road restrictions.

The students were part of a Destined for a Dream Foundation group, Talmedge said. Officials with the Bristol, Pa.-based group, a nonprofit that helps underprivileged youth, had no immediate comment on the crash.

The group's Facebook page said the trip to Harvard was to "visit the campus, sit with the office of cultural advancement, followed by a tour of the campus ... followed by Harvard Square (shopping, eating, site seeing...etc...) This should be a fun time for all!"

The bus suffered significant damage in the crash.

State police said at least 32 people were injured, including three seriously. Photos posted on the Fire Department's website showed firefighters standing on the top of the bus using boards to extract people. The last victim was freed from the bus around 9 p.m., according to the department.

The Massachusetts Bay Transportation Authority sent buses to pick up non-injured passengers and get them out of the frigid temperatures.

Soldiers Field Road curves along the Charles River and passes by Harvard and Boston University. It is a major roadway to the Massachusetts Turnpike.

Source: http://news.yahoo.com/bus-hits-overpass-boston-injuring-more-30-034112168.html

new jersey nets nba playoff schedule rondo morris claiborne mothers day gifts clippers lisa lampanelli

Saturday, February 2, 2013

After first three fighters are over, UFC 156 fighters make weight

The start of the UFC 156 weigh-ins was shaky, as the first three fighters were overweight. Was there a problem with the scale provided by the Nevada State Athletic Commission? Nah, the first three fighters were just overweight. Everyone else on the card made weight with no trouble. Yves Edwards even weighed in while eating a Snickers bar. Here are the complete weigh-in results, thanks to MMA Junkie.

MAIN CARD (Pay-per-view, 10 p.m. ET)
? Champ Jose Aldo (145) vs. Frankie Edgar (144)
? Rashad Evans (206) vs. Antonio Rogerio Nogueira (206)
? Alistair Overeem (264) vs. Antonio Silva (262)
? Jon Fitch (171) vs. Demian Maia (170)
? Joseph Benavidez (126) vs. Ian McCall (125)
PRELIMINARY CARD (FX, 8 p.m. ET)
? Evan Dunham (155) vs. Gleison Tibau (155)
? Jay Hieron (168) vs. Tyron Woodley (170)
? Bobby Green (155) vs. Jacob Volkmann (156)
? Yves Edwards (155) vs. Isaac Vallie-Flagg (156)
PRELIMINARY CARD (Facebook, 7 p.m. ET)
? Chico Camus (134) vs. Dustin Kimura (139.5)
? Edwin Figueroa (137.5) vs. Francisco Rivera (137)

A UFC spokesperson said Kimura will not weigh in again. He will be fined 20 percent of his purse. Figueroa weighed in again and was 136. Rivera still has time to make weight.

Source: http://sports.yahoo.com/blogs/mma-cagewriter/first-three-fighters-over-ufc-156-fighters-weight-011305149--mma.html

nj transit PSEG hocus pocus hocus pocus mta schedule PECO Hurricane Sandy update

Fourth Child on the Way for Tracy Morgan

The actor and comedian and his model fianc?e Megan Wollover, 26, are expecting their first child together, they confirm to PEOPLE exclusively.

Source: http://feeds.celebritybabies.com/~r/celebrity-babies/~3/OzJJb3-MBxg/

Arlen Specter Winsor McCay Amanda Todd washington nationals Gary Collins bus driver uppercut Argo

Selena Gomez: Sexy in the Studio!

Source: http://www.thehollywoodgossip.com/2013/01/selena-gomez-sexy-in-the-studio/

green book some like it hot duke university whale shark whale shark platypus platypus

Authorities release photo of accused Ala. abductor

MIDLAND CITY, Ala. (AP) ? After four anxious days, only the slimmest of details has come to light in a police standoff with an Alabama man who is accused of holding a 5-year-old boy hostage in a bunker, a sign of just how delicate the negotiations are.

Police have used a ventilation pipe to the underground bunker to talk to the man and deliver the boy medication for his emotional disorders, but they have not revealed how often they are in touch or what the conversations have been about. And authorities waited until Friday ? four days after the siege began ? to confirm what was widely known in this age of instant communication: The man accused of killing a school bus driver and abducting the boy Tuesday was 65-year-old Jimmy Lee Dykes, a Vietnam-era veteran who was known to neighbors as a menacing figure.

While much of what is going on inside the bunker remains a mystery, local officials who have spoken to police or the boy's family have described a small room with food, electricity and a TV. And while the boy has his medication, an official also said he has been crying for his parents.

Meanwhile, Midland City residents held out hope that the standoff would end safely and mourned for the slain bus driver and his family. Candlelight vigils have been held nightly at a gazebo in front of City Hall. Residents prayed, sang songs such as "Amazing Grace" and nailed homemade wooden crosses on the gazebo's railings alongside signs that read: "We are praying for you."

"We're doing any little thing that helps show support for him," said 15-year-old Taylor Edwards said.

Former hostage negotiators said authorities must be cautious and patient as long as they are confident that the boy is unharmed. Ex-FBI hostage negotiator Clint Van Zandt advised against any drastic measures such as cutting the electricity or putting sleep gas inside the bunker because it could agitate Dykes.

The negotiator should try to ease Dykes' anxieties over what will happen when the standoff ends, and refer to both the boy and Dykes by their first names, he said.

"I want to give him a reason to come out," Van Zandt said, "and my reason is, 'You didn't mean that to happen. It was unintentional. It could have happened to anyone. It was an accident. People have accidents, Jimmy Lee. It's not that big a thing. You and I can work that out.'"

Police seemed to be following that pattern. At a brief news conference to release a photo of Dykes, they brushed off any questions about possible charges.

"It's way too early for that," said Kevin Cook, a spokesman for the Alabama state troopers.

The shelter is about 4 feet underground, with about 6-by-8 feet of floor space and there is a PVC pipe that negotiators were speaking through.

One of Dykes' next-door neighbors said he spent two or three months constructing the bunker, digging several feet into the ground and then building a structure of lumber and plywood, which he covered with sand and dirt.

Neighbor Michael Creel said Dykes put the plastic pipe underground from the bunker to the end of his driveway so he can hear if anyone drives up to his gate. When Dykes finished the shelter a year or so ago, he in invited Creel to see it and he did.

"He was bragging about it. He said, 'Come check it out," Creel said.

He said he believes Dykes' goal with the standoff is a chance to publicize his political beliefs.

"I believe he wants to rant and rave about politics and government," Creel said. "He's very concerned about his property. He doesn't want his stuff messed with."

Midland City Mayor Virgil Skipper said he has been briefed by law enforcement agents and has visited with the boy's parents.

"He's crying for his parents," he said. "They are holding up good. They are praying and asking all of us to pray with them."

State Rep. Steve Clouse, who represents the Midland City area, said he visited the boy's mother and she is "hanging on by a thread." Clouse said the mother told him that the boy has Asperger's syndrome as well as attention deficit hyperactivity disorder, or ADHD.

Dr. Nadine Kaslow, a family therapist and psychiatry professor at Emory University in Atlanta, said the boy's emotional troubles might make things even more difficult for him.

"They have less way to make sense of things," she said of children with Asperger's and ADHD. "He may be less able to even interact with the person who's holding him hostage than another child might be, and he's less able, for example, to imagine friends that might be there waiting for him, to remember the good things, positive times. Also, he may be more likely to be frightened and overwhelmed and confused by the situation."

The normally quiet red-clay road leading to the bunker was busy Friday with more than a dozen police cars and trucks, a fire truck, a helicopter, officers from multiple agencies and news media near Midland City, a town with a population of 2,300 that's about 100 miles southeast of Montgomery.

Police vehicles have come and gone steadily for hours from the command post, a small church nearby.

Dykes was known around the neighborhood as a menacing figure who neighbors said once beat a dog to death with a lead pipe, threatened to shoot children for setting foot on his property and patrolled his yard at night with a flashlight and a firearm.

He was in the Navy from 1964 to 1969 and served some time in Japan, according to military records.

Authorities said Dykes boarded a stopped school bus filled with children on Tuesday afternoon and demanded two boys between 6 and 8 years old. When the driver tried to block his way, the gunman shot him several times and took the 5-year-old boy.

The bus driver, Charles Albert Poland Jr., 66, was hailed by locals as a hero who gave his life to protect the pupils on his bus.

Dykes had been scheduled to appear in court Wednesday to answer charges he shot at his neighbors in a dispute last month over a speed bump. Neighbor Claudia Davis said he yelled and fired shots at her and her family over damage Dykes claimed their pickup truck did to a makeshift speed bump in the dirt road. No one was hurt.

Davis' son, James Davis Jr., believed Tuesday's shooting was connected to the court date. "I believe he thought I was going to be in court and he was going to get more charges than the menacing, which he deserved, and he had a bunch of stuff to hide and that's why he did it."

Creel said his father and Dykes are friends. Creel said that after Dykes' arrest, Dykes wrote a 2- to 3-page letter that at least in part addressed the menacing case and that he shared with Greg Creel.

Michael Creel said he hasn't seen the letter but that his father has. The younger Creel said his father told him that Dykes said he had sent the letter to the local media, politicians and Alabama's governor.

Michael Creel said police on Friday took the copy of the letter from the Creels' home. Reached for comment, Greg Creel confirmed the existence of the letter but declined further comment and said he was cooperating with police.

A neighbor directly across the street, Brock Parrish, said Dykes usually wore overalls and glasses and his posture was hunched-over. He said Dykes usually drove a run-down "creeper" van with some of the windows covered in aluminum foil.

Parrish often saw him digging in his yard, as if he were preparing to lay down a driveway or building foundation. He lived in a small camping trailer and patrolled his lawn at night, walking from corner to corner with a flashlight and a long gun. Parrish described the weapon as an assault rifle, while another neighbor said it was a shotgun. Michael Creel said Dykes has five weapons he knows of, but he's not aware of him having an assault weapon. Authorities have not disclosed what firearms Dykes might have in his possession.

___

Associated Press writers Eric Tucker in Washington; Phillip Rawls in Midland City; Bob Johnson in Montgomery, Ala., and AP researcher Rhonda Shafner in New York contributed to this report.

Source: http://news.yahoo.com/authorities-release-photo-accused-ala-abductor-215324625.html

the village dallas fort worth tornado dallas tornadoes dallas weather nike nfl uniforms ben and jerrys free cone day tornado in dallas texas

Friday, February 1, 2013

Gut microbes at root of severe malnutrition in kids

Jan. 30, 2013 ? A study of young twins in Malawi, in sub-Saharan Africa, finds that bacteria living in the intestine are an underlying cause of a form of severe acute childhood malnutrition.

The research, led by Washington University School of Medicine in St. Louis and reported Feb. 1 in the journal Science, shows how dysfunctional communities of gut microbes conspire with a poor diet to trigger malnutrition.

The discovery is bolstered by additional studies in mice, showing that gut microbes transplanted from malnourished children cause dramatic weight loss and alter metabolism when the animals are fed a nutrient-poor diet.

"The gut microbes of malnourished children and malnourished mice do not appear to mature along a normal, healthy trajectory," says senior author Jeffrey Gordon, MD, director of the Center for Genome Sciences & Systems Biology. "Feeding the children and the mice a high-calorie, nutrient-rich food had a temporary, beneficial effect on their gut microbes, but not enough to repair the dysfunction. Our results suggest we need to devise new strategies to repair gut microbial communities so these children can experience healthy growth and reach their full potential."

Childhood malnutrition is a common problem in Malawi, and while a poor diet clearly plays a critical role, it is not the only factor. Scientists have long puzzled over why some children are afflicted by the condition but not others, even those in the same household who eat the same foods. This has led to the realization that a lack of food alone cannot explain its causes.

The standard treatment is a peanut-based, nutrient-rich therapeutic food, which has helped to reduce deaths from the condition. But the new study shows that the therapeutic food only has a transient effect on the gut microbes. Once the therapeutic food is discontinued, the community of microbes in the intestine and their genes revert to an immature state, in the children and in the mice.

This may explain why many malnourished children gain weight when they are treated with therapeutic food but remain at high risk for stunted growth, neurological problems and even malnutrition and death after treatment is stopped, the researchers say.

The new study followed 317 sets of twins in Malawi for the first three years of their lives. During this time, half of the twin pairs remained healthy, and in the others, either one or both twins developed malnutrition. The researchers focused on children who developed a form of malnutrition called kwashiorkor. The illness is associated with swollen bellies, liver damage, skin ulcerations and loss of appetite, in addition to wasting.

The researchers were particularly interested in twin pairs in which one twin remained healthy and the other became malnourished. This occurred just as often in fraternal twins as identical twins, pointing to a factor other than human genes.

So, Gordon and his team looked to another source of genes -- the microbial genes in the gut. These genes extract nutrients and calories from the diet, synthesize vitamins and nutrients and help shape the immune system.

In Malawai, the typical diet consists of a corn-based porridge that lacks sufficient vitamins and minerals. When a child in the study became malnourished, the standard of care was to give both twins the therapeutic food to limit food sharing.

This allowed Gordon to track the gut microbes just before, during and after treatment with the therapeutic food. While the food seemed to kick start maturation of the gut microbiomes of the severely malnourished children, its benefits were only temporary. Four weeks after the therapeutic food was discontinued, the gut microbiomes of the malnourished children either failed to progress or even regressed, while those of the healthy co-twins continued to mature on a normal trajectory.

Delving deeper, the researchers transplanted the gut microbes from healthy and malnourished co-twins into groups of germ-free mice that had been raised under sterile conditions.

Mice transplanted with malnourished children's gut microbes and that ate a typical Malawian diet experienced substantial weight loss, while those that had the healthy twin's gut microbes and ate the same nutrient-deficient diet did not. And although the microbiomes of the "malnourished" mice did mature when they were fed the therapeutic food, they tended to revert to a malnourished state when the village diet was resumed.

Looking more closely, the researchers found that mice with the gut microbes transplanted from a malnourished twin carried some species of bacteria associated with human illnesses, including inflammatory bowel disease. Moreover, the combination of a nutrient-deficient diet and a malnourished microbiome altered carbohydrate and amino acid metabolism, and reduced the availability of sulfur, which may contribute to weight loss. In addition, a central metabolic pathway for extracting energy from food also was disrupted.

"These findings suggest that energy metabolism may be a bigger challenge for these children when they are exposed to a nutrient-deficient, low-calorie diet," Gordon says.

Moving forward, the researchers plan to conduct additional studies to further define the role of the gut microbes in severe malnutrition and explore ways to permanently repair the gut microbiome so sick children can overcome the long-term effects of severe malnutrition.

"There is much more work to do," Gordon says. "It may be that earlier or longer treatment with existing or next-generation therapeutic foods will enhance our ability to repair or prevent the problems associated with malnutrition.

"We are also exploring whether it is possible to supplement the therapeutic food with beneficial gut bacteria from healthy children, as a treatment to repair the gut microbiome," he explains. "We hope that these studies will provide a new way of understanding how the gut microbiome and food interact to affect the health and recovery of malnourished children."

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by Washington University School of Medicine. The original article was written by Caroline Arbanas.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Smith, MI, Yatsunenko T, Manary MJ, Trehan I, Gordon J et al. Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor. Science, Feb. 1, 2013 DOI: 10.1126/science.1229000

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/rIxJTK6RKF4/130130184320.htm

jonbenet ramsey jason campbell doobie brothers jennie garth peter facinelli marques colston golden state warriors free agents nfl 2012

Sincerely Stacie: Book Review: Iconic Spirits by Mark Spivak

This blog offers reviews as well as giveaways. Each post will explain the compensation related to that review and/or giveaway. There are also various links on this website that are part of an affiliate program. I may receive compensation based on purchases through that link. Everthing on my site offers items that either I or my family could benefit from. I wouldn't offer anything that we wouldn't use or enjoy ourselves.

Source: http://www.sincerelystacie.com/2013/01/book-review-iconic-spirits-by-mark.html

december 21 2012 norad 12/21/12 bruno mars winter solstice Jabari Parker 2012